Blood Test Could Confirm Drug Success Against Alzheimer’s

A blood test that measures a specific protein in the blood could confirm a drug’s success against Alzheimer’s disease, a long-term study reports.
This non-invasive blood test is the only way to track the progress of Alzheimer’s disease. This test is designed to measure a blood protein called neuro-filament light.
What led scientists to this blood protein?

Previous studies had already demonstrated that blood levels of neuro-filament light are higher in people with diseases, such as Alzheimer’s Alzheimer’s disease destroys nerve cells and tissue in the brain. To date, no drug has been effective in stopping this disease. The question posed here is how to measure whether any drug is effective or not.

 

A previous study showed that measuring neuro-filament proteins in the blood identified Alzheimer’s years before emergence of symptoms. These symptoms include a decline in thinking and memory.

 

According to figures from the Alzheimer’s Association, there are 5.8 million people living with Alzheimer’s disease in the United States, and this number is likely to rise to just under 14 million by 2050.

 

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A Blood Test: Cheap, Easy, Non-Invasive, Accurate

A blood test to measure whether a drugs effectiveness against Alzheimer’s is an easy, cheap, non-invasive and accurate technique.

 

In this study, 1583 participants gave regular blood samples for 11 years during 2005–2016. Analysis measured the neuro-filament light levels.

 

Results showed that levels of neuro-filament proteins in the blood increased over time in patients diagnosed with Alzheimer’s disease. This was corroborated by brain scans and spinal fluid markers.

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